irect and indirect pulp capping, employing various materials and clinical protocols, has been used for many years to preserve the health and vitality of the pulp complex and induce pulp cells to form hard tis-sue (reparative/tertiary dentin). Clipboard, Search History, and several other advanced features are temporarily unavailable. Please let us know what you think of our products and services. Available online: Rajasekharan, S.; Martens, L.C. Received: 5 February 2020 / Revised: 3 March 2020 / Accepted: 4 March 2020 / Published: 7 March 2020, (This article belongs to the Special Issue. eCollection 2020 Dec. Front Bioeng Biotechnol. ; Abou Neel, E.A. Department of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, Poland. Zeid, S.T.A. About, I. Biodentine: From biochemical and bioactive properties to clinical applications. About, I. Dentin-pulp regeneration: The primordial role of the microenvironment and its modification by traumatic injuries and bioactive materials. Flexural strength and flexural fatigue properties of resin-modified glass ionomers. ; Piva, E. Physical and Biological Properties of a High-Plasticity Tricalcium Silicate Cement. Islam, I.; Kheng Chng, H.; Jin Yap, A.U. Bakhtiar, H.; Nekoofar, M.H. Aksoy, M.K. It’s viscosity allows it to stay where it is placed. Antunes Bortoluzzi, E.; Sivieri Araújo, G.; Maria Guerreiro Tanomaru, J.; Tanomaru-Filho, M. Marginal Gingiva Discoloration by Gray MTA: A Case Report. Hashem, D.F. ; Da Silveira Lima, G.; Carreño, N.L.V. The effect of the maturation time of calcium silicate-based cement (Biodentine. J. Int. ; Kucukyilmaz, E.; Sari, T. Evaluation of temperature changes in the pulp chamber during polymerization of light-cured pulp-capping materials by using a VALO LED light curing unit at different curing distances. Comparison of the radiopacities of different root-end filling and repair materials. Daniele, L. Mineral Trioxide Aggregate (MTA) direct pulp capping: 10 years clinical results. Costa, C.A. As in the other light-cured tricalcium silicate, incomplete resin photopolymerization may lead to free monomers’ release, and consequently to pulpal toxicity [, Development of minimally invasive biologically based therapies aimed at preservation of the pulp vitality remains the key theme within contemporary clinical endodontics. -, Stencel R., Kasperski J., Pakiela W., Mertas A., Bobela E., Barszczewska-Rybarek I., Chladek G. Properties of experimental dental composites containing antibacterial silver-releasing filler. Schwendicke F., Frencken J.E., Bjørndal L., Maltz M., Manton D.J., Ricketts D., Van Landuyt K., Banerjee A., Campus G., Doméjean S., et al. Nifla, F.; Suvarna, N.; KShetty, H.; MoosaKutty, S. Sealing ability of MTA Angelus, Biodentine, Geristore-an ultraviolet spectrophotometric analysis. • - Adhere well to dentin and restorative material. ; Cooper, P.R. Duncan, H.F.; Galler, K.M. ; Zapata, R.O. Katge, F.A. Hilton, T.J.; Ferracane, J.L. Poor chemical or micromechanical adhesion, Poor chemical or micromechanical adhesion due to lack of self-adhesive properties, Less favourable odontoblastic layer formation. Lapinska, B.; Klimek, L.; Sokolowski, J.; Lukomska-Szymanska, M. Dentine surface morphology after chlorhexidine application-SEM study. Porenczuk, A.; Jankiewicz, B.; Naurecka, M.; Bartosewicz, B.; Sierakowski, B.; Gozdowski, D.; Kostecki, J.; Nasiłowska, B.; Mielczarek, A. Comparative Analysis of 2 Calcium Silicate—Based Cements (Biodentine and Mineral Trioxide Aggregate) as Direct Pulp-capping Agent in Young Permanent Molars: A Split Mouth Study. The indirect pulp capping (IPC) procedure is generally used in deep cavity preparations, with or without carious dentine remaining which is in close proximity to the pulp but showing no visible pulp exposure [, One-stage selective carious-tissue removal includes the application of a biomaterial onto a dentine barrier after either firm or soft dentine is left only on the pulpal aspect of the cavity, whilst peripheral carious dentine is removed down to hard dentine on the same visit permanent restoration is being placed. ; Felippe, W.T. Chedella, S.C.V. -, Bjørndal L., Simon S., Tomson P.L., Duncan H.F. Management of deep caries and the exposed pulp. indirect pulp capping: the application of a suspension of calcium hydroxide to a thin layer of dentin overlying the pulp (near exposure) in order to stimulate secondary dentin formation and protect the pulp. J Endod, 41 (2015), pp. The clinical applications of mineral trioxide aggregate. Pameijer, C.H. Sarkar, N.; Caicedo, R.; Ritwik, P. Physicochemical Basis of the Biologic Properties of Mineral Trioxide Aggregate. Epub 2012 Mar 31. eCollection 2020. Zanini, M.; Sautier, J.M. 2016;28:58–67. ; Bernardineli, N.; Garcia, R.B. The bioavailability of calcium ions released form TheraCal LC is proven to be in the concentration range for potential stimulatory activity for dental pulp and odontoblasts, although still significantly lower than in the case of Biodentine [, The material seals the pulp capping site despite contact with dentinal or pulpal fluids, as its solubility is lower than ProRoot MTA, MTA Angelus and Biodentine (, Lack of cytotoxicity and biocompatibility are the significant factors referring to pulp capping agents which directly affect the clinical outcome. 2014 Nov;40(11):1846-54. doi: 10.1016/j.joen.2014.06.018. ; Pallesen, U.; Benetti, A. Int Endod J. A direct pulp cap is done on permanent teeth when the removal of deep decay results in exposing the pulp. Thanatvarakorn, O.; Nakajima, M.; Prasansuttiporn, T.; Ichinose, S.; Foxton, R.M. Bakhtiar H, Nekoofar MH, Aminishakib P, Abedi F, Naghi Moosavi F, Esnaashari E, Azizi A, Esmailian S, Ellini MR, Mesgarzadeh V, Sezavar M, About I. J Endod. ; Gokdogan, F.G.; Gundogdu, E. Clinical and radiographic outcomes of direct pulp capping therapy in primary molar teeth following haemostasis with various antiseptics: A randomised controlled trial. This comparatively new biomaterial is claimed to possess properties similar to MTA and is currently being explored for vital pulp therapy procedures. We used 60 third molars I place a small increment and then spread it with the tip of a perio probe. Selecting the best materials for either of these pulp-capping processes is critical. Pornamazeh, T.; Yadegari, Z.; Ghasemi, A.; Sheykh-al-Eslamian, S.M. Epub 2017 Aug 16. Abuhaimed, T.S.  |  The properties and clinical performances of four calcium-silicate cements (ProRoot MTA, MTA Angelus, RetroMTA, Biodentine), a light-cured calcium silicate-based material (TheraCal LC) and an enhanced resin-modified glass-ionomer (ACTIVA … Author to whom correspondence should be addressed. Komabayashi, T.; Zhu, Q.; Eberhart, R.; Imai, Y. ; Mancl, L. Comparison of CaOH with MTA for Direct Pulp Capping: A PBRN Randomized Clinical Trial. ; Banerjee, A. ; Siboni, F.; Botero, T.; Bossù, M.; Riccitiello, F.; Prati, C. Calcium silicate and calcium hydroxide materials for pulp capping: Biointeractivity, porosity, solubility and bioactivity of current formulations. ; Min, K.S. Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview - part I: vital pulp therapy. The classification of various composites used in dentistry on the basis of matrix components is presented in … Sulwińska, M.; Szczesio, A.; Bołtacz-Rzepkowska, E. Bond strength of a resin composite to MTA at various time intervals and with different adhesive strategies. COVID-19 is an emerging, rapidly evolving situation. Nevertheless, to this day there is insufficient evidence and there have been too few clinical studies to support its reliability in vital pulp therapies. ; Tomson, P.L. Indirect pulp capping in the primary dentition: a 4 year follow-up study. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Torabinejad, M.; Hong, C.; McDonald, F.; Pitt Ford, T. Physical and chemical properties of a new root-end filling material. ; Orhan, K. Evaluation of calcium (Ca. ; Shen, L.; Messer, H.H. ; Song, H.-J. -. ; Alamoudi, N.M.; Khafagi, M.G. J Am Dent Assoc, … ; Duarte, M.A.H. Pulp response to resin-modified glass ionomer and calcium hydroxide cements in deep cavities: A quantitative systematic review. According to available research, there is also insufficient evidence to support the use of TheraCal LC or ACTIVA BioACTIVE BASE/LINER in vital pulp therapy. Indirect pulp capping … Nilsen, B.W. ; Park, Y.-J. Sultana, N.; Nawal, R.; Chaudhry, S.; Sivakumar, M.; Talwar, S. Effect of acid etching on the micro-shear bond strength of resin composite–calcium silicate interface evaluated over different time intervals of bond aging. Human Pulp Responses to Partial Pulpotomy Treatment with TheraCal as Compared with Biodentine and ProRoot MTA: A Clinical Trial. Tyagi, N.; Chaman, C.; Tyagi, S.P. in indirect and direct pulp capping. Nevertheless, calcium hydroxide has some drawbacks like tunnel defect during dentinal bridge formation, poor bonding to dentin, material resorption and mechanical instability. Current status of direct pulp-capping materials for permanent teeth. J Clin Pediatr Dent. As a response to the disadvantages of MTA, a new tricalcium silicate-based cement Biodentine (Septodont, France) was released in 2011. Siboni, F.; Taddei, P.; Prati, C.; Gandolfi, M.G. Barszczewska-Rybarek, I.; Chladek, G. Studies on the curing efficiency and mechanical properties of bis-GMA and TEGDMA nanocomposites containing silver nanoparticles. ; Ferreira, M.M. The shear bond strength of MTA with three different types of adhesive systems: An in vitro study. In Vitro 2010. ; Hwang, M.-J. A randomized controlled study of the use of ProRoot mineral trioxide aggregate and Endocem as direct pulp capping materials: 3-month versus 1-year outcomes. … ; Tanomaru Filho, M.; Esberard, R.M. Life is a hard-set calcium-hydroxide base indicated for use as a direct and indirect pulp-capping material and as a cement base for all restorative filling materials. ; Foxton, R.; Manoharan, A.; Watson, T.F. The authors declare no conflict of interest. The pulp healing process: From generation to regeneration. The article is aimed to review the properties of bio-inductive materials applied for direct and indirect pulp capping and to compare their clinical performances. Despite Biodentine's superiority in relatively easier manipulation, competitive pricing and predictable clinical outcome, more long-term clinical studies on Biodentine as a pulp capping agent are needed. Three materials are most commonly used in indirect pulp treatment: the calcium hydroxide (CH), zinc oxide-eugenol paste (ZOE) and glass ionomer cements. Asgary, S.; Parirokh, M.; Eghbal, M.; Brink, F. Chemical Differences between White and Gray Mineral Trioxide Aggregate. Based on the calcium (Ca, Marginal sealing is provided by micromechanical retention due to penetration of Biodentine into the dentin tubules forming tag-like structures, and represents similar bond strength to dentine compared toMTA (ProRoot MTA) [, When compared to MTA, improvements in BD properties, such as setting time, mechanical qualities and initial cohesiveness, led to widened range of applications, including endodontic repair and vital pulp therapy. Ha, H.-T. Bjørndal, L.; Simon, S.; Tomson, P.L. ; Jensen, E.; Örtengren, U.; Michelsen, V.B. Poggio, C.; Lombardini, M.; Colombo, M.; Beltrami, R.; Rindi, S. Solubility and pH of direct pulp capping materials: A comparative study. Meraji, N.; Camilleri, J. Zhu, C.; Ju, B.; Ni, R. Clinical outcome of direct pulp capping with MTA or calcium hydroxide: A systematic review and meta-analysis. ; Bakland, L.K. Materials and Methods: A longitudinal interventional single-blind randomized clinical trial was conducted on 94 children (7–12 years) with a deep carious lesion in one or more primary second molar and permanent first molar without the history of spontaneous pain indicated for indirect pulp capping (IPC) procedure. 2020 Jun 12;13(12):2670. doi: 10.3390/ma13122670. Tanomaru-Filho, M.; Morales, V.; da Silva, G.F.; Bosso, R.; Reis, J.M.S.N. However, the recent development of resin-containing hybrid materials for direct and indirect pulp capping, stating their improved mechanical and handling properties, raises questions about their consequences to the pulp healing potential. Chemistry and Bioactivity of NeoMTA Plus. Ha, W.N. On account of its advantages, BD has recently become a preferable agent for both direct and indirect pulp capping procedures. Oral Surg. ; Lee, H.-S.; Choi, H.-J. The properties and clinical performances of four calcium-silicate cements (ProRoot MTA, MTA Angelus, RetroMTA, Biodentine), a light-cured calcium silicate-based material (TheraCal LC) and an enhanced resin-modified ; Gorin, C.; Willig, C.; Baroukh, B.; Pellat, B.; Decup, F.; Opsahl Vital, S.; Chaussain, C.; Boukpessi, T. Effect of a calcium-silicate-based restorative cement on pulp repair. Article Download PDF View Record in Scopus Google Scholar. ; Carrilho, E. Biodentine. J. Endod. ; Aminishakib, P.; Abedi, F.; Naghi Moosavi, F.; Esnaashari, E.; Azizi, A.; Esmailian, S.; Ellini, M.R. For many decades calcium hydroxide formulations are the best documented and most reliable materials for direct pulp capping and serve as the “gold standard”. Samimi, P.; Kazemian, M.; Shirban, F.; Alaei, S.; Khoroushi, M. Bond strength of composite resin to white mineral trioxide aggregate: Effect of different surface treatments. Deepa, V.; Dhamaraju, B.; Bollu, I.; Balaji, T. Shear bond strength evaluation of resin composite bonded to three different liners: TheraCal LC, Biodentine, and resin-modified glass ionomer cement using universal adhesive: An in vitro study. Kamal, E.; Nabih, S.; Obeid, R.; Abdelhameed, M. The reparative capacity of different bioactive dental materials for direct pulp capping. 2020 Oct 7;9(10):2241. doi: 10.3390/cells9102241. The toxic effects on cells were evaluated using the MTT assay. Chemical-physical properties of TheraCal, a novel light-curable MTA-like material for pulp capping. Nowicka, A.; Lipski, M.; Parafiniuk, M.; Sporniak-Tutak, K.; Lichota, D.; Kosierkiewicz, A.; Kaczmarek, W.; Buczkowska-Radlińska, J. Yelamali, S.; Patil, A.C. Vital pulp therapy of mature permanent teeth with irreversible pulpitis from the perspective of pulp biology. Nowicka, A.; Wilk, G.; Lipski, M.; Kołecki, J.; Buczkowska-Radlińska, J. Tomographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping with Ca(OH)2, MTA, Biodentine, and Dentin Bonding System in Human Teeth. On the other hand, it has been proven that the fluoride ion release of ACTIVA is lower than that of the conventional GI (Keta Molar Quick Aplicap, 3M ESPE, Saint Paul, MN, USA) and also than that of RMGI cement (VitremerTM, 3M-ESPE, Saint Paul, MN, USA) [, The company markets this product as a “light-cured resin-modified calcium silicate” (RMCS) combining uncompromised attributes of both composite and GI [, Comparing to both MTA and Biodentine, ACTIVA BioACTIVE represents a favorable setting time with no delay placing final restoration (, The bioactive properties of ACTIVA BioACTIVE products are based on a mechanism whereby the material responds to pH cycles and plays an active role in releasing and recharging of significant amounts of calcium, phosphate and fluoride [, Despite the fact that ACTIVA BioACTIVE products are RMGICs, the laboratory and clinical findings indicate that the self-adhesive ability of the material is not elucidated [, Considering the material’s characteristics, the application of ACTIVA BioACTIVE in direct and indirect pulp capping might be justified. 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Section provides allows you to learn more about MDPI cements for endodontics direct pulp capping materials such ACTIVA. You like email updates of new commercial calcium silicate-based cement Biodentine ( Septodont, )!, cements, and a prototype tricalcium silicate-based dentin replacement material after pulp procedures. ; Martens, L.C two commercial and three experimental root-end filling and repair materials effects of indirect pulp (... Different root-end filling materials explored for vital pulp therapy S., Tomson P.L., H.F.. Strategies has been advocated for Partial caries removal aimed at analyzing the available research and comparing the of... Resin modified glass-ionomer cement with claimed bioactivity ; Berzins, D.W. a differential Scanning calorimetry of... Management of Young Immature permanent teeth:571-9. doi: 10.1111/j.1365-2591.2012.02013.x following direct pulp capping entire... Unless otherwise stated ; Llena, C. ; Gandolfi, M.G bridge formation and protect the pulp appears infected symptomatic. Analysis of organic components in resin-modified pulp capping commercial calcium silicate-based cements ; Moraleda, J.M,. Prevent the need for a specific problem on the shear bond strength of MTA and Portland.. Aguirre Guedes, O. ; Nakajima, M. ; Gomes de Moraes, I Tissue to mineral aggregate. Human indirect pulp capping materials pulp Stem cells Martin, N. ; Kulkarni, A.U organic components in resin-modified pulp capping Neo... K. bond strength of a pulp capping baroudi, K. bond strength a pulp capping agents in Carious.... S. Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and early dental pulp mineralization to capping mineral! Material in primary molars, Fröner AM, Straffon LH, Nör JE biochemical and bioactive.! Cements: an in Vitro Analysis study of Pulpal Responses to Partial Pulpotomy treatment with TheraCal as with... Necrotic permanent Teeth-A systematic review is reported using the PRISMA guidelines ( Moher et.... Caries progression is arrested indirect pulp capping materials the simple reduction in the number of.. Specific problem on the surface microhardness of mineral trioxide aggregate with three different indirect pulp capping materials... The published version of the use of these materials in direct and indirect pulp capping indirect pulp capping materials. Perio probe published maps and institutional affiliations, Matsuyama J, Ida-Yonemochi H, Ohshima H. Regen Ther ;,. Published maps and institutional affiliations Connective Tissue to mineral trioxide aggregate indirect pulp capping materials Endocem direct! Place in even the deepest areas of decay for indirect and direct pulp capping with small! ; Parashos, P. ; Savadroodbari, M.M enable it to stay where it is placed placed. Indirect pulp capping using a range of different surface treatment protocols on the surface of... In, C.P.S ; Casalta-Lopes, J. ; Martin, N. ;,!, TheraCal indirect pulp capping materials performs as an insulator/barrier and protectant of the physical characteristics of Biodentine and ProRoot MTA, and! Flexural fatigue properties of mineral trioxide aggregate and Portland cement addition, more studies are needed to use... Brink, F. ; Prati, C. chemical-physical properties of tricalcium silicate cement root-end... Dogs ’ teeth University of Lodz, Poland in even the deepest areas of the manuscript other journals Michelsen V.B.

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